Assessment of the photoprotection properties of sunscreens by chromatographic measurement of DNA damage in skin explants.

@article{Mouret2011AssessmentOT,
  title={Assessment of the photoprotection properties of sunscreens by chromatographic measurement of DNA damage in skin explants.},
  author={St{\'e}phane Mouret and Patrick Bogdanowicz and M J Haure and Nathalie Castex-Rizzi and Jean Cadet and Alain Favier and Thierry Douki},
  journal={Photochemistry and photobiology},
  year={2011},
  volume={87 1},
  pages={109-16}
}
Evaluation of the photoprotection provided by sunscreens is performed either through the induction of erythema and expressed as the sun protection factor (SPF), or by the UVA-mediated persistent pigment darkening (PPD). None of these two endpoints has a link with skin cancer, the most deleterious consequence of excess exposure to solar UV radiation. We thus set up a complementary approach to evaluate the protection provided by sunscreens to the genome of human skin. This is based on the… CONTINUE READING