Assessment of the neurogenic flare reaction in small-fiber neuropathies.

@article{Bickel2002AssessmentOT,
  title={Assessment of the neurogenic flare reaction in small-fiber neuropathies.},
  author={Andreas Bickel and Heidrun Helga Kr{\"a}mer and Max J Hilz and F. Birklein and Bernhard Neundoerfer and Martin Schmelz},
  journal={Neurology},
  year={2002},
  volume={59 6},
  pages={917-9}
}
To improve sensitivity of the analysis of axon reflex flare reaction, the authors used a laser Doppler scanner and analyzed flare intensity and size induced by histamine iontophoresis simultaneously at the foot and thigh in patients with small-fiber neuropathy (n = 10) and controls (n = 9). Flare size, but not laser Doppler flux, clearly distinguished patients from controls at both locations (p < 0.01) and may be useful for evaluation of small-fiber neuropathies. 

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