Assessment of the multiple discriminative stimulus effects of ethanol using an ethanol-pentobarbital-water discrimination in rats.

@article{Bowen1997AssessmentOT,
  title={Assessment of the multiple discriminative stimulus effects of ethanol using an ethanol-pentobarbital-water discrimination in rats.},
  author={Carrie A. Bowen and Gomes Gatto and Kathleen A. Grant},
  journal={Behavioural pharmacology},
  year={1997},
  volume={8 4},
  pages={
          339-52
        }
}

• Carrie A. Bowen, Gomes Gatto, Kathleen A. Grant
• Published 1997 in Behavioural pharmacology

Previous drug discrimination studies have elucidated the importance of gamma-aminobutyric acidA (GABAA), N-methyl-D-aspartate (NMDA) glutamate, and serotonin (5-HT) receptor systems in mediating the discriminative stimulus effects of ethanol. The present study used a three-choice operant drug discrimination procedure in an attempt to determine if salient GABAergic effects could be separated from other stimulus effects of 2.0 g/kg ethanol. Adult male Long-Evans rats (n = 7) were trained to… CONTINUE READING

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