Assessment of the effect of haematocrit-dependent arterial input functions on the accuracy of pharmacokinetic parameters in dynamic contrast-enhanced MRI.

@article{Just2011AssessmentOT,
  title={Assessment of the effect of haematocrit-dependent arterial input functions on the accuracy of pharmacokinetic parameters in dynamic contrast-enhanced MRI.},
  author={Nathalie Just and Dow-Mu Koh and James A d'Arcy and David J. Collins and Martin O. Leach},
  journal={NMR in biomedicine},
  year={2011},
  volume={24 7},
  pages={902-15}
}
The detection and prognosis of prostate cancer in its early stages are critically important. It is therefore essential to improve the existing dynamic contrast-enhanced MRI (DCE MRI) techniques commonly used for the assessment of the tumour vascular environment. The goal of this study was to describe a method for the estimation of the arterial input function (AIF) in DCE MRI by measuring R(2) * values in the femoral artery of patients with early-stage prostate cancer. The calculation of… CONTINUE READING