Assessment of the catabolic effects of interleukin-1beta on proteoglycan metabolism in equine cartilage cocultured with synoviocytes.

@article{Gregg2006AssessmentOT,
  title={Assessment of the catabolic effects of interleukin-1beta on proteoglycan metabolism in equine cartilage cocultured with synoviocytes.},
  author={Abigail J Gregg and Lisa A Fortier and H. O. Mohammed and Karen G Mayr and Brian John Miller and Jennifer L Haupt},
  journal={American journal of veterinary research},
  year={2006},
  volume={67 6},
  pages={957-62}
}
OBJECTIVE To evaluate the effects of interleukin (IL)-1beta on proteoglycan metabolism in equine cartilage explants when cultured in the presence of synoviocytes. SAMPLE POPULATION Samples of cartilage and synovium collected from the femoropatellar joints of three 2- to 3-year-old horses. PROCEDURES 3 experimental groups were established: cartilage explants only, synoviocytes only, and cartilage explants-synoviocytes in coculture. In each group, samples were cultured with or without IL… CONTINUE READING