Assessment of the cardiostimulant action of propionyl-L-carnitine on chronically volume-overloaded rat hearts


Chronic volume overload was induced in young rats of Wistar strain by surgical opening of the aorto-caval fistula. Three months later, during in vitro perfusions with exogenous palmitate, left ventricular function and energy turnover (QO2) of hypertrophied hearts were severely depressed. This seemed to be related to impaired long-chain fatty acid… (More)
DOI: 10.1007/BF00880159


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