Assessment of synthetic chimeric multiple antigenic peptides for diagnosis of GB virus C infection.

@article{Gmara2010AssessmentOS,
  title={Assessment of synthetic chimeric multiple antigenic peptides for diagnosis of GB virus C infection.},
  author={Mar{\'i}a Jos{\'e} G{\'o}mara and Leticia Fern{\'a}ndez and Teresa P{\'e}rez and Guadalupe Ercilla and Isabel Haro},
  journal={Analytical biochemistry},
  year={2010},
  volume={396 1},
  pages={51-8}
}
The use of synthetic peptides of both structural and nonstructural proteins of GB virus C (GBV-C) has been studied for the development of new systems to diagnose infection caused by this virus. In an attempt to increase the antigenicity of linear peptide sequences, chimeric multiple antigenic peptides (MAPs) containing epitopes from E2, NS4, and NS5 GBV-C proteins have been synthesized. The synthetic constructs were evaluated by ELISA to establish whether the epitopes in chimeric branched… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 49 references

A novel lysine-protecting procedure for continuous-flow solid-phase synthesis of branched peptides

  • B. W. Bycroft, W. C. Chan, S. R. Chhabra, N. D. Hone
  • J. Chem. Soc. Chem. Commun
  • 1993
Highly Influential
3 Excerpts

Comparative study of SPR and ELISA methods based on analysis of CD 166 / ALCAM levels in cancer and control human sera

  • V. M. Faca Vaisocherova, A. D. Taylor, S. Hanash, S. Jiang
  • Liver Int .
  • 2009

Similar Papers

Loading similar papers…