Assessment of solubilization characteristics of different surfactants for carvedilol phosphate as a function of pH.

@article{Chakraborty2009AssessmentOS,
  title={Assessment of solubilization characteristics of different surfactants for carvedilol phosphate as a function of pH.},
  author={Subhashis Chakraborty and Dali Shukla and Achint Jain and Brahmeshwar Mishra and Sanjay Singh},
  journal={Journal of colloid and interface science},
  year={2009},
  volume={335 2},
  pages={242-9}
}
The effect of surfactants on the solubility of a new phosphate salt of carvedilol was investigated at different biorelevent pH to evaluate their solubilization capacity. Solutions of different classes of surfactants viz., anionic-sodium dodecyl sulfate (SDS) and sodium taurocholate (STC), cationic-cetyltrimethylammonium bromide (CTAB) and non-ionic-Tween 80 (T80) were prepared in the concentration range of 5-35 mmol dm(-3) in buffer solutions of pH 1.2, 3.0, 4.5, 5.8, 6.8 and 7.2. The… CONTINUE READING
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