Assessment of skin barrier function and biochemical changes of ex vivo human skin in response to physical and chemical barrier disruption.

Abstract

Topical dermatotherapy is intended to be used on diseased skin. Novel drug delivery systems even address differences between intact and diseased skin underlining the need for pre-clinical assessment of different states of barrier disruption. Herein, we studied how short-term incubation in culture media compared to incubation in humidified chambers affects… (More)
DOI: 10.1016/j.ejpb.2016.12.012

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Cite this paper

@article{Dge2017AssessmentOS, title={Assessment of skin barrier function and biochemical changes of ex vivo human skin in response to physical and chemical barrier disruption.}, author={Nadine D{\"{o}ge and Araks Avetisyan and Sabrina Hadam and Eva Katharina Barbosa Pfannes and Fiorenza Rancan and Ulrike Blume-Peytavi and Annika Vogt}, journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V}, year={2017}, volume={116}, pages={138-148} }