Assessment of response of brain metastases to radiotherapy by PET imaging of apoptosis with 18F-ML-10

@article{Allen2012AssessmentOR,
  title={Assessment of response of brain metastases to radiotherapy by PET imaging of apoptosis with 18F-ML-10},
  author={Aaron M Allen and Miri Ben-Ami and Ayelet Reshef and Adam P. Steinmetz and Yulia Kundel and Edna Inbar and Ruth Djaldetti and Tal Davidson and Eyal Fenig and Ilan Ziv},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2012},
  volume={39},
  pages={1400-1408}
}
Early assessment of tumor response to therapy is vital for treatment optimization for the individual cancer patient. Induction of apoptosis is an early and nearly universal effect of anticancer therapies. The purpose of this study was to assess the performance of 18F-ML-10, a novel PET radiotracer for apoptosis, as a tool for the early detection of response of brain metastases to whole-brain radiation therapy (WBRT). Ten patients with brain metastases treated with WBRT at 30 Gy in ten daily… CONTINUE READING

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