Assessment of respiratory mechanics in small animals: the simpler the better?

@article{Hantos2002AssessmentOR,
  title={Assessment of respiratory mechanics in small animals: the simpler the better?},
  author={Zolt{\'a}n Hantos and Vito Brusasco},
  journal={Journal of applied physiology},
  year={2002},
  volume={93 4},
  pages={1196-7}
}
THE RECENT INTEREST IN SMALL animal models, which are particularly suitable for genetic and translational studies on the pathophysiology of bronchial asthma, has prompted the search for measurements of lung function that are easy to implement and, if possible, noninvasive. In 1997, Hamelmann et al. (6) proposed a plethysmographic method to assess airway responsiveness in mice, which eventually gained wide popularity. The experimental setup of this method is indeed extremely attractive: the… CONTINUE READING

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