• Corpus ID: 56579128

Assessment of pulmonary function in rheumatoid arthritis patients attending Rheumatology Clinics in Nairobi

  title={Assessment of pulmonary function in rheumatoid arthritis patients attending Rheumatology Clinics in Nairobi},
  author={I Biomdo and George Omondi Oyoo and Mecha Jo and Muhwa J. Chakaya},
Background: Pulmonary involvement is a frequent and among the most severe extra-articular manifestations of Rheumatoid Arthritis (RA) ranking as the second cause of mortality in this patient population. Rheumatoid arthritis can a ect the lung parenchyma, airways and pleura. Pulmonary complications are directly responsible for 10-20% of all mortality in RA patients. Spirometry is becoming increasingly available in Kenya and could be used in peripheral areas to screen and monitor for pulmonary… 
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Abstract Aim of the work To investigate the frequency and types of pulmonary involvement using high resolution computed tomography (HRCT) and pulmonary function tests (PFTs) and to identify different
Rheumatoid Arthritis Associated Interstitial Lung Disease in KwaZulu-Natal, South Africa: A Retrospective 5-Year Review
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The prevalence of liver dysfunction in patients with rheumatoid arthritis is found to be high, at 57%, and recommends regular monitoring of liver function tests in patientsWith rheumatism, according to a cross-sectional descriptive study conducted at Kenyatta National Hospital.


Respiratory symptoms in rheumatoid arthritis: relation to pulmonary abnormalities detected by high-resolution CT and pulmonary functional testing
It is concluded that pulmonary involvement is a common manifestation in Egyptian RA patients, and the pattern of involvement is generally consistent with other studies that were performed worldwide.
Interstitial lung disease in recent onset rheumatoid arthritis.
In conclusion, changes consistent with ILD in early RA are frequent and the significance of these changes is being determined in a longitudinal study.
Pulmonary functions testing in patients with rheumatoid arthritis.
Serial PFT among patients with RA is indicated and allows for earlier identification of various ventilatory defects and Linear regression analyses failed to identify any patient or disease-specific characteristics that could predict a worsening in PFT.
Airway obstruction and rheumatoid arthritis.
Respiratory disorders (including bronchiectasis) and airway obstruction are more frequent among patients with rheumatoid arthritis than in rheumatic controls, and explanatory factors for obstruction included variables characterizing the rhearatoid arthritis.
[Pulmonary manifestation of rheumatoid arthritis].
  • H. Lioté
  • Medicine
    Revue des maladies respiratoires
  • 2008
Treatment is empirical and based on usual indications and on drugs used in idiopathic fibrosis and other connective tissue pulmonary pathologies, which strongly suggest a common pathogenic mechanism for RA in the joints and in other sites, such as the lung.
Respiratory symptoms and disease characteristics as predictors of pulmonary function abnormalities in patients with rheumatoid arthritis: an observational cohort study
Assessment of respiratory symptoms along with a limited number of clinical parameters may serve as a useful and inexpensive clinical tool for identifying RA patients in need of further pulmonary investigation.
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Abnormalities on chest examination or on full pulmonary function tests, even without restrictive changes or chest radiographic abnormalities, should prompt physicians to request a chest HRCT scan when investigating dyspnoea in patients with RA.
Cardiovascular risk factors in patients with rheumatoid arthritis at Kenyatta National Hospital
Screening of cardiovascular risk factors in patients with RA should be done routinely and a larger study with normal controls from the general population should be undertaken in order to measure this cardiovascularrisk factors and cardiovascular disease in this population.
Rheumatoid arthritis lung disease. Determinants of radiographic and physiologic abnormalities.
Although RA disease activity/severity (particularly as defined by the HAQ DI) was important, smoking was the most consistent independent predictor of radiographic and physiologic abnormalities suggestive of ILD in RA.
Airways involvement in rheumatoid arthritis: clinical, functional, and HRCT findings.
A high prevalence of airway abnormalities as assessed with high-resolution computed tomography and/or pulmonary function tests was observed in rheumatoid arthritis patients and HRCT appears to be more sensitive than PFTs for detecting small airways disease.