Assessment of protein structure refinement in CASP9.

@article{MacCallum2011AssessmentOP,
  title={Assessment of protein structure refinement in CASP9.},
  author={Justin L. MacCallum and Alberto P{\'e}rez and Michael J. Schnieders and Lan B Hua and Matthew P. Jacobson and Ken A. Dill},
  journal={Proteins},
  year={2011},
  volume={79 Suppl 10},
  pages={74-90}
}
We assess performance in the structure refinement category in CASP9. Two years after CASP8, the performance of the best groups has not improved. There are few groups that improve any of our assessment scores with statistical significance. Some predictors, however, are able to consistently improve the physicality of the models. Although we cannot identify any clear bottleneck in improving refinement, several points arise: (1) The refinement portion of CASP has too few targets to make many… CONTINUE READING
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