Assessment of priming of the human neutrophil respiratory burst.

  title={Assessment of priming of the human neutrophil respiratory burst.},
  author={Margarita Hurtado-Nedelec and Karama Makni-Maalej and Marie-Anne Gougerot-Pocidalo and Pham My-Chan Dang and Jamel El-Benna},
  journal={Methods in molecular biology},
Neutrophils play an essential role in host defense against microbial pathogens and in the inflammatory reaction. Upon activation, neutrophils produce reactive oxygen species (ROS) such as superoxide anion (O2 (∙-)), hydrogen peroxide (H2O2), and hypochlorous acid (HOCl), a process referred to as the respiratory burst. The enzyme responsible for this process is called the NADPH oxidase or respiratory burst oxidase. This multicomponent enzyme system is composed of two transmembrane proteins… CONTINUE READING

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