Assessment of platelet activation in several different anticoagulants by the Advia 120 Hematology System, fluorescence flow cytometry, and electron microscopy.

@article{Ahnadi2003AssessmentOP,
  title={Assessment of platelet activation in several different anticoagulants by the Advia 120 Hematology System, fluorescence flow cytometry, and electron microscopy.},
  author={Charaf E Ahnadi and E Sabrinah Chapman and Mariette L{\'e}pine and David Okrongly and N{\'u}ria Pujol-Moix and Angel Ram{\'o}n Hern{\'a}ndez and Faiza F Boughrassa and Andrew M. Grant},
  journal={Thrombosis and haemostasis},
  year={2003},
  volume={90 5},
  pages={940-8}
}
In vivo platelet activation results are often confounded by activation induced in vitro during the preparative procedures. We measured ex vivo (basal) and in vitro (thrombin-induced) platelet activation in sodium citrate, ethylenediaminetetraacetic acid (EDTA), and Citrate Theophylline Dipyridamole Adenosine (CTAD) whole blood specimens. Determinations were made by measurements of platelet density (mean platelet component: MPC concentration) on the Advia 120 Hematology System. The MPC has been… CONTINUE READING

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