Assessment of myocardial reactivity to controlled hypercapnia with free-breathing T2-prepared cardiac blood oxygen level-dependent MR imaging.

@article{Yang2014AssessmentOM,
  title={Assessment of myocardial reactivity to controlled hypercapnia with free-breathing T2-prepared cardiac blood oxygen level-dependent MR imaging.},
  author={H Yang and Roya Yumul and Richard Tang and Ivan Cokic and Michael Klein and Avinash Kali and Olivia Sobczyk and Behzad Sharif and Jun Tang and Xiaoming Bi and Sotirios A. Tsaftaris and Debiao Li and Antonio Hernandez Conte and J A Fisher and Rohan Dharmakumar},
  journal={Radiology},
  year={2014},
  volume={272 2},
  pages={397-406}
}
PURPOSE To examine whether controlled and tolerable levels of hypercapnia may be an alternative to adenosine, a routinely used coronary vasodilator, in healthy human subjects and animals. MATERIALS AND METHODS Human studies were approved by the institutional review board and were HIPAA compliant. Eighteen subjects had end-tidal partial pressure of carbon dioxide (PetCO2) increased by 10 mm Hg, and myocardial perfusion was monitored with myocardial blood oxygen level-dependent (BOLD) magnetic… CONTINUE READING

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