Assessment of morphology, antigenicity, and nucleic acid integrity for diagnostic thyroid pathology using formalin substitute fixatives.

  title={Assessment of morphology, antigenicity, and nucleic acid integrity for diagnostic thyroid pathology using formalin substitute fixatives.},
  author={Sandra Lassalle and V{\'e}ronique J Hofman and I. Marius and Virginie Gavric-Tanga and Patrick Brest and Katia Havet and Catherine Butori and Eric Selva and Jos{\'e} Santini and Baharia Mograbi and Paul Hofman},
  journal={Thyroid : official journal of the American Thyroid Association},
  volume={19 11},
  • S. Lassalle, V. Hofman, P. Hofman
  • Published 4 November 2009
  • Medicine, Biology
  • Thyroid : official journal of the American Thyroid Association
BACKGROUND With the advent of the formaldehyde standard law in France, and because of the impact of new methods for diagnosis and prognosis in pathology, formalin replacement in surgical pathology laboratories is currently being discussed in France. However, a set of criteria must be assessed before introducing a formalin substitute fixative. The objective of this study was to compare formalin substitute fixation with formalin fixation and cryoconservation of tissues from several benign and… 

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