Assessment of lipid, hepatic, and thyroid parameters with serum perfluorooctanoate (PFOA) concentrations in fluorochemical production workers

  title={Assessment of lipid, hepatic, and thyroid parameters with serum perfluorooctanoate (PFOA) concentrations in fluorochemical production workers},
  author={Geary W. Olsen and Larry R. Zobel},
  journal={International Archives of Occupational and Environmental Health},
  • G. OlsenL. R. Zobel
  • Published 29 June 2007
  • Medicine
  • International Archives of Occupational and Environmental Health
ObjectivesPerfluorooctanoic acid (PFOA) results in peroxisome proliferator mediated effects in rats and mice resulting in hypolipidemia but not in monkeys. Counterintuitive modestly positive associations between PFOA and cholesterol levels in production workers have been inconsistently reported. The purpose of this assessment was to examine this association in male workers who manufactured or used PFOA at three facilities.MethodsSubjects were male employee voluntary participants of a… 

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