Assessment of ligand-binding residue predictions in CASP9.

  title={Assessment of ligand-binding residue predictions in CASP9.},
  author={Tobias Schmidt and J{\"u}rgen Haas and Tiziano Gallo Cassarino and Torsten Schwede},
  volume={79 Suppl 10},
Interactions between proteins and their ligands play central roles in many physiological processes. The structural details for most of these interactions, however, have not yet been characterized experientially. Therefore, various computational tools have been developed to predict the location of binding sites and the amino acid residues interacting with ligands. In this manuscript, we assess the performance of 33 methods participating in the ligand-binding site prediction category in CASP9… CONTINUE READING