Assessment of in vivo metabolism in failing hearts using hyperpolarised 13C magnetic resonance

Abstract

Purpose The aim of this study was to monitor carbohydrate metabolism alongside cardiac structure and function, throughout HF progression. Methods Dilated cardiomyopathy (DCM) was induced in pigs (n = 4) by rapid ventricular pacing at 188 bpm for 4-5 weeks. Pigs were examined at baseline and at weekly time points throughout DCM progression. At each time… (More)

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