Assessment of immunobiological effects induced by chemicals, drugs or food additives. I. Tier testing and screening approach.

@article{Dean1979AssessmentOI,
  title={Assessment of immunobiological effects induced by chemicals, drugs or food additives. I. Tier testing and screening approach.},
  author={Jack H. Dean and M L Padarathsingh and Thomas R. Jerrells},
  journal={Drug and chemical toxicology},
  year={1979},
  volume={2 1-2},
  pages={5-17}
}
The indications of immunologic dysfunction following low level exposure of rodents or even man to certain chemicals and drugs have raised concern regarding methodology and approaches for routine assessment of immunobiological effects. The immunogiological effect observed may either indicate impaired immunopotentiation or hypersensitization. The assays selected for testing should be relevant to the human experience and adaptable to certain practical considerations such as cost, reproducibility… CONTINUE READING