Assessment of genomic damage in colorectal cancer by DNA fingerprinting: prognostic applications.

@article{Arribas1997AssessmentOG,
  title={Assessment of genomic damage in colorectal cancer by DNA fingerprinting: prognostic applications.},
  author={Rosario Arribas and G. Capella and Silvia T{\'o}rtola and Laia Masramon and William E. Grizzle and M. Herma Perucho and Miguel A. Peinado},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1997},
  volume={15 10},
  pages={3230-40}
}
PURPOSE Here we evaluate the prognostic significance of the relative value of genomic damage assessed by DNA fingerprinting in colorectal cancer. MATERIALS AND METHODS Sixty-three tumor and paired normal mucosa samples were included in the study. Genomic damage was assessed by comparative analysis of paired normal and tumor tissue DNA fingerprints by the arbitrarily primed polymerase chain reaction (AP-PCR). Decreases and increases of intensity in bands were computed and referred to the total… CONTINUE READING

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