Assessment of gastric carcinoma risk associated with Helicobacter pylori may vary depending on the antigen used: CagA specific enzyme-linked immunoadsorbent assay (ELISA) versus commercially available H. pylori ELISAs.

@article{Maeda2000AssessmentOG,
  title={Assessment of gastric carcinoma risk associated with Helicobacter pylori may vary depending on the antigen used: CagA specific enzyme-linked immunoadsorbent assay (ELISA) versus commercially available H. pylori ELISAs.},
  author={Shin Maeda and Hiroshi Yoshida and Keiji Ogura and Yutaka Yamaji and Tsuneo Ikenoue and Toru Mitsushima and H Tagawa and Rie Kawaguchi and Kazuhiko Mori and Ken ichi Mafune and Takao Kawabe and Yoshimune Shiratori and Masao Omata},
  journal={Cancer},
  year={2000},
  volume={88 7},
  pages={1530-5}
}
BACKGROUND Previous epidemiologic studies produced inconsistent results when examining the relation between Helicobacter pylori infection and the risk of gastric carcinoma by measuring various anti-H. pylori antibodies. This study investigated the increased risk of cancer by examining different antibodies, including the specific anti-CagA antibody and antibodies from two commercially available kits. METHODS An ELISA for the detection of serum anti-CagA was established using a recombinant CagA… CONTINUE READING

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