Assessment of evidence for K+-H+ exchange in isolated type-1 cells of neonatal rat carotid body

Abstract

 Intracellular pH (pHi) was measured in enzymically isolated, neonatal rat carotid body type-1 cells, using the fluorophore carboxy-SNARF-1 (AM-loaded), and using the nigericin technique for in situ fluorescence calibration (nigericin is a membrane-soluble K+-H+ exchanger). In CO2/HCO3 –-free media, inhibiting Na+-H+ exchange produced a prompt fall of pHi… (More)
DOI: 10.1007/s004240050417

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