Assessment of epidermal growth factor receptor and K-ras mutation status in cytological stained smears of non-small cell lung cancer patients: correlation with clinical outcomes.

@article{Lozano2011AssessmentOE,
  title={Assessment of epidermal growth factor receptor and K-ras mutation status in cytological stained smears of non-small cell lung cancer patients: correlation with clinical outcomes.},
  author={Mar{\'i}a Dolores Ru{\'i}z Lozano and Javier J Zulueta and Jos{\'e} Ignacio Echeveste and Alfonso G{\'u}rpide and Luis Seijo and Salvador Mart{\'i}n-Algarra and Anabel del Barrio and Rub{\'e}n P{\'i}o and Miguel {\'A}ngel Idoate and Tania Labiano and Jose Luis Perez-Gracia},
  journal={The oncologist},
  year={2011},
  volume={16 6},
  pages={877-85}
}
OBJECTIVE Epidermal growth factor receptor (EGFR) and K-ras mutations guide treatment selection in non-small cell lung cancer (NSCLC) patients. Although mutation status is routinely assessed in biopsies, cytological specimens are frequently the only samples available. We determined EGFR and K-ras mutations in cytological samples. METHODS DNA was extracted from 150 consecutive samples, including 120 Papanicolau smears (80%), 10 cell blocks (7%), nine fresh samples (6%), six ThinPrep® tests (4… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 14 times over the past 90 days. VIEW TWEETS
35 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Similar Papers

Loading similar papers…