Assessment of environmental enteropathy in the MAL-ED cohort study: theoretical and analytic framework.

@article{Kosek2014AssessmentOE,
  title={Assessment of environmental enteropathy in the MAL-ED cohort study: theoretical and analytic framework.},
  author={Margaret N. Kosek and Richard Littleton Guerrant and Gagandeep Kang and Zulfiqar Ahmed Bhutta and Pablo Pe{\~n}ataro Yori and Jean Gratz and Michael Gottlieb and Dennis R. Lang and Gwenyth O Lee and Rashidul Haque and Carl J Mason and Tahmeed Ahmed and Aldo {\^A}ngelo M Lima and William A Petri and Eric R Houpt and Maribel Paredes Ol{\'o}rtegui and Jessica C. Seidman and Estomih Mduma and Amidou Samie and S. Narasimha Rao Babji},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2014},
  volume={59 Suppl 4},
  pages={S239-47}
}
Individuals in the developing world live in conditions of intense exposure to enteric pathogens due to suboptimal water and sanitation. These environmental conditions lead to alterations in intestinal structure, function, and local and systemic immune activation that are collectively referred to as environmental enteropathy (EE). This condition, although poorly defined, is likely to be exacerbated by undernutrition as well as being responsible for permanent growth deficits acquired in early… CONTINUE READING