Assessment of efficacy of a bivalent BTV-2 and BTV-4 inactivated vaccine by vaccination and challenge in cattle.

@article{Savini2009AssessmentOE,
  title={Assessment of efficacy of a bivalent BTV-2 and BTV-4 inactivated vaccine by vaccination and challenge in cattle.},
  author={Giovanni Savini and Claude Hamers and Annalea Conte and Pasquale Migliaccio and Barbara Bonfini and Liana Teodori and Mauro Di Ventura and Pascal Hudelet and Carla Schumacher and Vincenzo Caporale},
  journal={Veterinary microbiology},
  year={2009},
  volume={133 1-2},
  pages={1-8}
}
The efficacy of a bivalent inactivated vaccine against bluetongue virus (BTV) serotypes 2 (BTV-2) and 4 (BTV-4) was evaluated in cattle by general and local examination, serological follow-up, and challenge. Thirty-two 4-month-old calves were randomly allocated into 2 groups of 16 animals each. One group was vaccinated subcutaneously (s/c) with two injections of bivalent inactivated vaccine at a 28-day interval, and the second group was left unvaccinated and used as control. Sixty-five days… CONTINUE READING

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Study of the safety and efficacy of a recombinant vaccine for bluetongue virus

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