Assessment of efficacy and psychomotor performances of thiocolchicoside and tizanidine in patients with acute low back pain

@article{Ketenci2005AssessmentOE,
  title={Assessment of efficacy and psychomotor performances of thiocolchicoside and tizanidine in patients with acute low back pain},
  author={Ayşeg{\"u}l Ketenci and Elif Ozcan and Sacit Karamursel},
  journal={International Journal of Clinical Practice},
  year={2005},
  volume={59}
}
Objectives of this study were to assess efficacy and effects on psychomotor performances of thiocolchicoside (TCC) and tizanidine (TZ) compared to placebo. 
[A systematic review of using myorelaxants in treatment of low back pain].
TLDR
There are enough data to confirm the efficacy of myorelaxants in treatment of nonspecific low back pain, myore laxants are recommended as monotherapy or in combination with analgesics or NSAID, the nonsedative drugs tolperisone or thiocolchicoside should be preferred.
Clinical Comparative Study: Efficacy and Tolerability of Tolperisone and Thiocolchicoside in Acute Low Back Pain and Spinal Muscle Spasticity
TLDR
Tolperisone is an effective and well tolerated option for treatment of patients with skeletal muscle spasm associated with pain and in comparison with Thiocolchicoside in the treatment of acute low back pain with spasm of spinal muscles.
Effects of Mephenoxalone and Tizanidine for Acute Painful Spasm of Paravertebral Muscles: A Randomized Double-Blind Control Study
TLDR
This randomized, doubleblind study demonstrates equivalent treatment efficacies of mephenoxalone and tizanidine in alleviating symptoms of acute painful paravertebral muscle spasms in Taiwanese patients.
COMPARATIVE EFFICACY AND SAFETY OF METHOCARBAMOL AND THIOCOLCHICOSIDE IN ACUTE LOW BACK PAIN.
TLDR
It is concluded that either methocarbamol or thiocolchicoside in combination with paracetamol are effective in acute LBP with spasm.
Muscle relaxants--the current position in the treatment of spasticity in orthopedics.
TLDR
Combining muscle relaxants with analgesics significantly improves the effectiveness of the treatment and allows to reduce drugs doses.
Evaluation of efficacy and tolerability of eperisone and thiocolchicoside in treatment of low back pain associated with muscle spasm: An open label, prospective, randomized controlled trial -
TLDR
Eperisone is an effective muscle relaxant with equivalent efficacy compared to Thiocolchicoside, and has a better tolerability in treatment of low back pain with muscle spasm.
A Comparative study of efficacy of Thiocolchicoside with Diclofenac vs Eperisone with Diclofenac in patients with back pain
TLDR
The Eperisone with dicl ofenac was found to be more effective in terms of Finger floor distance and improvement in Lasegue’s sign, VAS score and global assessment scale than Thiocolchicoside with Diclofenac.
Efficacy and safety of a fixed combination of intramuscular diclofenac 75 mg + thiocolchicoside 4 mg in the treatment of acute low back pain: a phase III, randomized, double blind, controlled trial.
TLDR
A 5-day treatment with IM diclofenac+thiocolchicoside FDC in a 4-mL volume was as effective and well tolerated as the separate injection of the two components in improving pain symptoms in patients with acute moderate-severe LBP.
Effects of three different conservative treatments on pain, disability, quality of life, and mood in patients with cervical spondylosis
TLDR
Exercise treatment has an important role in achieving long-term recovery of problems occurring with cervical spondylosis and it was determined that patient satisfaction did not change in the 1st and 2nd group, but decreased in the 3rd group during long- term follow-up.
The efficacy of topical thiocolchicoside (Muscoril) in the treatment of acute cervical myofascial pain syndrome: a single-blind, randomized, prospective, phase IV clinical study.
TLDR
Thiocolchicoside can be used in the treatment of myofascial pain syndrome and the ointment form may be a good alternative, particularly in patients who cannot receive injections.
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