Assessment of early treatment response to neoadjuvant chemotherapy in breast cancer using non-mono-exponential diffusion models: a feasibility study comparing the baseline and mid-treatment MRI examinations

@inproceedings{Bedair2016AssessmentOE,
  title={Assessment of early treatment response to neoadjuvant chemotherapy in breast cancer using non-mono-exponential diffusion models: a feasibility study comparing the baseline and mid-treatment MRI examinations},
  author={Reem Bedair and Andrew N Priest and Andrew J. Patterson and Mary Ann McLean and Martin J. Graves and Roido Manavaki and Andrew Bruce Gill and Oshaani Abeyakoon and John R. Griffiths and Fiona J. Gilbert},
  booktitle={European Radiology},
  year={2016}
}
To assess the feasibility of the mono-exponential, bi-exponential and stretched-exponential models in evaluating response of breast tumours to neoadjuvant chemotherapy (NACT) at 3 T. Thirty-six female patients (median age 53, range 32–75 years) with invasive breast cancer undergoing NACT were enrolled for diffusion-weighted MRI (DW-MRI) prior to the start of treatment. For assessment of early response, changes in parameters were evaluated on mid-treatment MRI in 22 patients. DW-MRI was… CONTINUE READING

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