Assessment of cytotoxic and immunomodulatory properties of four antidepressants on primary cultures of abalone hemocytes (Haliotis tuberculata).

@article{Minguez2014AssessmentOC,
  title={Assessment of cytotoxic and immunomodulatory properties of four antidepressants on primary cultures of abalone hemocytes (Haliotis tuberculata).},
  author={La{\"e}titia Minguez and Marie-Pierre Halm-Lemeille and Katherine Costil and Ronan Bureau and J. D. Lebel and Antoine Serpentini},
  journal={Aquatic toxicology},
  year={2014},
  volume={153},
  pages={3-11}
}
Pharmaceutical compounds like antidepressants found in surface waters raise concerns due to their potential toxicity on non-target aquatic organisms. This study aimed at investigating the in vitro cytotoxicity and immunomodulatory properties of four common antidepressants, namely Amitriptyline, Clomipramine, Citalopram and Paroxetine, on primary cultures of abalone hemocytes (Haliotis tuberculata), after 48 h-exposure. Effects on immunocompetence (phagocytosis, levels of reactive oxygen species… CONTINUE READING

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