Assessment of cross-reactivity between Mycobacterium bovis and M. kansasii ESAT-6 and CFP-10 at the T-cell epitope level.

@article{Vordermeier2007AssessmentOC,
  title={Assessment of cross-reactivity between Mycobacterium bovis and M. kansasii ESAT-6 and CFP-10 at the T-cell epitope level.},
  author={Hans Martin Vordermeier and Jemma Brown and Paul J. Cockle and Willeke P. J. Franken and Jan Wouter Drijfhout and Sandra M. Arend and Tom H. M. Ottenhoff and Keith J Jahans and R. Glyn Hewinson},
  journal={Clinical and vaccine immunology : CVI},
  year={2007},
  volume={14 9},
  pages={1203-9}
}
Cross-reactivity between Mycobacterium kansasii ESAT-6 and CFP-10 homologues and their M. bovis counterparts can confound the interpretation of immunodiagnostic tests for tuberculosis. M. kansasii is a nontuberculous mycobacterial species cultured from skin test-positive cattle in Great Britain. Using peptides derived from M. bovis and M. kansasii ESAT-6 and CFP-10 regions that differ between these species, we investigated the species specificity and cross-reactivity at the level of individual… CONTINUE READING
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