Assessment of cortical damage in early multiple sclerosis with quantitative T2 relaxometry.

@article{Gracien2016AssessmentOC,
  title={Assessment of cortical damage in early multiple sclerosis with quantitative T2 relaxometry.},
  author={R. M. Gracien and S. C. Bosch Reitz and Stephanie-Michelle Hof and Vinzenz Fleischer and Hilga Maria Zimmermann and Amgad Droby and Helmuth Steinmetz and Frauke Zipp and Ralf Deichmann and Johannes C. Klein},
  journal={NMR in biomedicine},
  year={2016},
  volume={29 4},
  pages={
          444-50
        }
}
T2 relaxation time is a quantitative MRI in vivo surrogate of cerebral tissue damage in multiple sclerosis (MS) patients. Cortical T2 prolongation is a known feature in later disease stages, but has not been demonstrated in the cortical normal appearing gray matter (NAGM) in early MS. This study centers on the quantitative evaluation of the tissue parameter T2 in cortical NAGM in a collective of early MS and clinically isolated syndrome (CIS) patients, hypothesizing that T2 prolongation is… CONTINUE READING
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