Assessment of closed-loop ventilatory stability in obstructive sleep apnea

  title={Assessment of closed-loop ventilatory stability in obstructive sleep apnea},
  author={Musa H. Asyali and Richard B. Berry and Michael C. K. Khoo},
  journal={IEEE Transactions on Biomedical Engineering},
Previous studies on ventilatory control in obstructive sleep apnea (OSA) have generally indicated depressed chemosensitivity, implying greater stability of the chemical control of breathing in these subjects. However, these results were based on tests involving steady-state or quasi-steady measurements obtained in wakefulness. We have developed a method for assessing the dynamic stability characteristics of chemoreflex control in OSA patients during sleep. While continuous positive airway… CONTINUE READING
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