Assessment of cancellous bone quality in severe osteoarthrosis: bone mineral density, mechanics, and microdamage.

@article{Fazzalari1998AssessmentOC,
  title={Assessment of cancellous bone quality in severe osteoarthrosis: bone mineral density, mechanics, and microdamage.},
  author={Nicola L. Fazzalari and Mark R. Forwood and Kyle Smith and Bodo Manthey and P G Herreen},
  journal={Bone},
  year={1998},
  volume={22 4},
  pages={381-8}
}
The role of bone microdamage (microscopic cracks or microcracks and ultrastructural collagen matrix and bone mineral damage) in diseases such as osteoarthrosis and osteoporosis is poorly understood. Microdamage accumulation in vivo is influenced by age and cyclic loading, therefore, it would be useful if the burden of microdamage in bone could be assessed by noninvasive measures such as the radiological measurement of bone mineral density (BMD). The aim of this study was to investigate the… CONTINUE READING

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