Assessment of butadiene exposure in synthetic rubber manufacturing workers in Texas using frequencies of hprt mutant lymphocytes as a biomarker.

@article{Ward2001AssessmentOB,
  title={Assessment of butadiene exposure in synthetic rubber manufacturing workers in Texas using frequencies of hprt mutant lymphocytes as a biomarker.},
  author={Jonathan B Ward and S. Z. Abdel-Rahman and Rogene F. Henderson and Thomas H. Stock and Maria Grazia Morandi and Judah I Rosenblatt and Marinel M Ammenheuser},
  journal={Chemico-biological interactions},
  year={2001},
  volume={135-136},
  pages={465-83}
}
1,3-Butadiene (BD), which is used to manufacture synthetic rubber, is a mutagen and carcinogen. Because past occupational exposures have been associated with an increased risk of leukemia, there has been a dramatic reduction in workplace exposure standards. The health benefits of these reduced levels of occupational exposure to BD will be difficult to evaluate using relatively insensitive traditional epidemiological studies; however, biomarkers can be used to determine whether there are… CONTINUE READING

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