Assessment of bovine mammary chemokine gene expression in response to lipopolysaccharide, lipotechoic acid + peptidoglycan, and CpG oligodeoxynucleotide 2135.

@article{Mount2009AssessmentOB,
  title={Assessment of bovine mammary chemokine gene expression in response to lipopolysaccharide, lipotechoic acid + peptidoglycan, and CpG oligodeoxynucleotide 2135.},
  author={Jeremy A Mount and Niel Alexander Karrow and Jeff L Caswell and Herman J. Boermans and Ken E. Leslie},
  journal={Canadian journal of veterinary research = Revue canadienne de recherche veterinaire},
  year={2009},
  volume={73 1},
  pages={49-57}
}
During intramammary infections pathogen associated molecular patterns (PAMPs) induce an inflammatory response, recognized clinically as mastitis. Recognition of PAMPs by mammary cells leads to the production of the pro-inflammatory cytokines, TNF-alpha and IL-1beta. These cytokines augment the secretion of various chemokines that are responsible for directing the host cellular immune response, and consequently the outcome of infection. Previous research has shown that gram-negative and gram… CONTINUE READING