Assessment of benzodiazepine receptor heterogeneity in vivo: apparent pA2 and pKB analyses from behavioral studies

@article{Rowlett1996AssessmentOB,
  title={Assessment of benzodiazepine receptor heterogeneity in vivo: apparent pA2 and pKB analyses from behavioral studies},
  author={James K. Rowlett and William L. Woolverton},
  journal={Psychopharmacology},
  year={1996},
  volume={128},
  pages={1-16}
}
Abstract The purpose of this review was to establish in vivo apparent pA2 and pKB values for antagonism of the discriminative stimulus effects of benzodiazepine ligands, and to compare these values to those obtained from other behavioral procedures. Articles were chosen from the Medline data base from January 1976 to August 1995. This literature consisted of studies with flumazenil (Ro 15–1788) as the antagonist, as well as other benzodiazepine ligands (β-carbolines, CGS 9896, CGS 8216). The… CONTINUE READING

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