Assessment of antibiotic levels in lung tissue with erosion-controlled dosage forms


The concentration-time curve of ciprofloxacin has been assessed in the blood compartment and in the lung tissue following oral administration of the drug. Immediate release and erosion-controlled dosage forms have been examined. A numerical model based on finite differences and taking into account all relevant data has been built: the kinetics of drug… (More)
DOI: 10.1007/BF03189813


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