Assessment of an optimized mycobacterial interspersed repetitive- unit-variable-number tandem-repeat typing system combined with spoligotyping for population-based molecular epidemiology studies of tuberculosis.

@article{Oelemann2007AssessmentOA,
  title={Assessment of an optimized mycobacterial interspersed repetitive- unit-variable-number tandem-repeat typing system combined with spoligotyping for population-based molecular epidemiology studies of tuberculosis.},
  author={Mara Cardoso Oelemann and Roland Diel and Vincent Vatin and W. Haas and Sabine Ruesch-Gerdes and Camille Locht and Stefan Niemann and Philip Supply},
  journal={Journal of clinical microbiology},
  year={2007},
  volume={45 3},
  pages={691-7}
}
An optimized set of 24 mycobacterial interspersed repetitive-unit-variable-number tandem-repeat (MIRU-VNTR) loci, including a discriminatory subset of 15 loci, has recently been defined for the typing of Mycobacterium tuberculosis. Here, we evaluated the performances of this MIRU-VNTR typing system in combination with spoligotyping for the detection of transmission chains in a population-based study comprising 91% of culture-confirmed tuberculosis patients reported in 2003 in Hamburg, Germany… CONTINUE READING
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Molecular epidemiology of tuberculosis among immigrants in Hamburg, Germany

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