Assessment of an Interferon-gamma release assay for the diagnosis of latent tuberculosis infection in haemodialysis patient.

@article{Hoffmann2010AssessmentOA,
  title={Assessment of an Interferon-gamma release assay for the diagnosis of latent tuberculosis infection in haemodialysis patient.},
  author={Matthias Hoffmann and Dimitrios Tsinalis and Pietro Vernazza and Walter Fierz and Isabelle Binet},
  journal={Swiss medical weekly},
  year={2010},
  volume={140 19-20},
  pages={286-92}
}
BACKGROUND The accurate diagnosis of latent tuberculosis infection (LTBI) in haemodialysis patients remains elusive. Impaired immune function associated with chronic kidney failure causes a high number of anergic tuberculin skin tests (TST). Interferon-gamma (INF-gamma) release assays (IGRAs) measuring the INF-gamma secretion of tuberculosis specific T-cells have several advantages over the TST but their significance in dialysis patients is currently uncertain. METHODS This study examines the… CONTINUE READING

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