Assessment of age modulated vascular inflammation in ApoE-/- mice by USPIO-enhanced magnetic resonance imaging.

@article{Sigovan2010AssessmentOA,
  title={Assessment of age modulated vascular inflammation in ApoE-/- mice by USPIO-enhanced magnetic resonance imaging.},
  author={Monica Sigovan and Amine Bessaad and Hasan Alsaid and Eric Lancelot and Claire A Corot and Bruno Neyran and Nicolas Provost and Zouher Majd and Magali Breisse and Emmanuelle Canet-Soulas},
  journal={Investigative radiology},
  year={2010},
  volume={45 11},
  pages={702-7}
}
OBJECTIVE Inflammation within atherosclerotic lesions increases the risk for plaque rupture and thrombosis. A functional approach to plaque analysis is the intravenous administration of ultrasmall superparamagnetic particles of iron oxide (USPIO) that enables visualization of macrophages residing in the plaques. In this study, we sought to characterize the age-related inflammatory status associated with atherosclerosis lesion progression in ApoE mice using USPIO-enhanced magnetic resonance… CONTINUE READING
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Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide

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