Assessment of adolescent neurotoxicity: rationale and methodological considerations.

  title={Assessment of adolescent neurotoxicity: rationale and methodological considerations.},
  author={Linda Patia Spear},
  journal={Neurotoxicology and teratology},
  volume={29 1},
This introduction to the special issue of Neurotoxicology and Teratology on "Risk of neurobehavioral toxicity in adolescence" begins by broadly considering the ontogeny and phylogeny of adolescence, and the potential value of animal models of adolescence. Major findings from the emerging neuroscience of adolescence are then highlighted to establish the importance of studies of adolescent neurotoxicity. A variety of methodological issues that are of particular relevance to adolescent exposures… CONTINUE READING

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