Assessment of a novel equine tarsocrural experimental joint disease model using recombinant interleukin-1β and arthroscopic articular sampling of the medial malleolus of the tibia on the standing sedated horse.

@article{Nelson2017AssessmentOA,
  title={Assessment of a novel equine tarsocrural experimental joint disease model using recombinant interleukin-1β and arthroscopic articular sampling of the medial malleolus of the tibia on the standing sedated horse.},
  author={B B Nelson and Melissa R King and David D. Frisbie},
  journal={Veterinary journal},
  year={2017},
  volume={229},
  pages={
          54-59
        }
}
Joint disease and osteoarthritis are common problems in the horse and numerous experimental studies have been developed to determine the safety and efficacy of new therapies. Synovitis, a critical component of joint disease, has been experimentally induced using recombinant interleukin-1 beta (reIL-1β) to investigate new joint therapies in a controlled environment, although the use of reIL-1β has not been reported in the equine tarsocrural joint. A common consequence of performing controlled… CONTINUE READING