Assessment of Thy-1 mRNA levels as an index of retinal ganglion cell damage.


PURPOSE Thy-1 is primarily, if not entirely, expressed by the ganglion cells within the retina. This knowledge was used to index ganglion cell death after ischemia and excitotoxicity by studying changes in Thy-1 mRNA levels. METHODS Insults to the rat retina were delivered either by elevation of intraocular pressure for 60 minutes or by intravitreal… (More)


2 Figures and Tables