Assessment of Therapeutic Efficacy and After Photodynamic Therapy Provides Early Noninvasive Monitoring of Murine Tumor Blood Flow During

Abstract

Purpose:Tomonitor tumor blood flownoninvasively duringphotodynamic therapy (PDT) and to correlate flow responses with therapeutic efficacy. Experimental Design: Diffuse correlation spectroscopy (DCS) was used to measure blood flow continuously in radiation-induced fibrosarcoma murine tumors during Photofrin (5 mg/kg)/ PDT (75mW/cm,135 J/cm). Relative blood… (More)

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