Study on Impact of Iron and Folic Acid on the Plasma Trace Minerals in Pregnant Anemic Women
Preeclampsia is one of the causes that lead to significant mortality among pregnant women and fetus. However it is etiology is unknown. The objective of this study was to assess the level of serum cadmium and manganese and their relation in development of preeclampsia. A case control hospital based study was conducted in Khartoum-Sudan, blood samples were collected from 50 preeclampsia and 50 normal pregnant women. Serum cadmium and manganese were determined using atomic absorption spectrophotometers. The study was conducted during the period of January to April 2015. The mean ± SD of serum cadmium and manganese respectively were (0.13±0.05, 0.14±0.04) for preeclampsia, while the mean ± SD of serum cadmium and manganese in normal pregnant women were (0.08±0.02, 0.42±0.1.0) respectively. Cadmium was significantly higher (p=0.00), were as manganese was significantly lower (p=0.00) in preeclampsia than in normal pregnant women. Preeclamptic patients have higher serum cadmium and lower manganese level when compared with normal pregnant women. It appears that increase serum cadmium and decrease in serum manganese may be related to the development of preeclampsia.