Assessment of QF-PCR as the first approach in prenatal diagnosis.

@article{Bdenas2010AssessmentOQ,
  title={Assessment of QF-PCR as the first approach in prenatal diagnosis.},
  author={C{\'e}lia B{\'a}denas and Laia Rodr{\'i}guez-Revenga and Carme Morales and Carmen Mediano and Alberto Plaja and Ma Mar P{\'e}rez-Iribarne and A. Soler and N{\'u}ria Clusellas and Antoni Borrell and M. {\'A}ngeles N{\'u}{\~n}ez S{\'a}nchez and Elisabeth Mir{\'o} and A. Tabuenca S{\'a}nchez and Montserrat Mil{\`a} and Wladimiro Jim{\'e}nez},
  journal={The Journal of molecular diagnostics : JMD},
  year={2010},
  volume={12 6},
  pages={828-34}
}
Quantitative fluorescent PCR (QF-PCR) has been used by many laboratories for prenatal diagnosis of the most common aneuploidies. QF-PCR is rapid, cost-effective, and suitable for automation and can detect most abnormalities diagnosed by conventional karyotyping. Whether QF-PCR should be used alone in most of the samples and in which karyotyping should also be offered is currently a topic of debate. We evaluated and compared the results obtained from 7679 prenatal samples in which conventional… CONTINUE READING

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