Assessment of JC Polyoma Virus in Colon Neoplasms

  title={Assessment of JC Polyoma Virus in Colon Neoplasms},
  author={G. Theodoropoulos and Dimitris Panoussopoulos and I. Papaconstantinou and M. Gazouli and M. Perdiki and J. Bramis and A. Lazaris},
  journal={Diseases of the Colon & Rectum},
  • G. Theodoropoulos, Dimitris Panoussopoulos, +4 authors A. Lazaris
  • Published 2005
  • Medicine
  • Diseases of the Colon & Rectum
  • PURPOSEResearch data have recently emphasized an intriguing association of JC polyoma virus with colon carcinogenesis. Tumorigenicity of JC virus is attributed to the T-antigen of its Mad-1 variant. Controversy arose when another research group did not confirm this association. The purpose of this study was to detect JC virus in a series of colon neoplasms from Greek patients.METHODSA nested polymerase chain reaction assay was used to detect JC virus in 80 cancerous, 25 adenomatous specimens of… CONTINUE READING

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    Publications referenced by this paper.
    Association of human polyomavirus JCV with colon cancer: evidence for interaction of viral T-antigen and beta-catenin.
    • 175
    • PDF
    Human neurotropic polyomavirus, JCV, and its role in carcinogenesis
    • 142
    • PDF
    JC virus DNA sequences are frequently present in the human upper and lower gastrointestinal tract.
    • 50
    JC virus DNA is present in the mucosa of the human colon and in colorectal cancers.
    • 203
    • Highly Influential
    • PDF
    Viruses and cancer: lessons from the human polyomavirus, JCV
    • 54
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    Detection and Differentiation of Human Polyomaviruses JC and BK by LightCycler PCR
    • 99
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    JC virus: a biomarker for colorectal cancer?
    • 7
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