Assessment of JC Polyoma Virus in Colon Neoplasms

@article{Theodoropoulos2005AssessmentOJ,
  title={Assessment of JC Polyoma Virus in Colon Neoplasms},
  author={George E Theodoropoulos and Dimitris Panoussopoulos and Ioannis Papaconstantinou and Maria Gazouli and Marina Perdiki and John Bramis and Andreas Lazaris},
  journal={Diseases of the Colon \& Rectum},
  year={2005},
  volume={48},
  pages={86-91}
}
PURPOSEResearch data have recently emphasized an intriguing association of JC polyoma virus with colon carcinogenesis. Tumorigenicity of JC virus is attributed to the T-antigen of its Mad-1 variant. Controversy arose when another research group did not confirm this association. The purpose of this study was to detect JC virus in a series of colon neoplasms from Greek patients.METHODSA nested polymerase chain reaction assay was used to detect JC virus in 80 cancerous, 25 adenomatous specimens of… Expand
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