Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinking.

  title={Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinking.},
  author={Michelle A. Tanchuck and N. Yoneyama and M. Ford and Andrea M. Fretwell and Deborah A. Finn},
  volume={45 1},
  • Michelle A. Tanchuck, N. Yoneyama, +2 authors Deborah A. Finn
  • Published 2011
  • Psychology, Medicine
  • Alcohol
  • Drinking to intoxication or binge drinking is a hallmark characteristic of alcohol abuse. Although hard to model in rodents, the scheduled high alcohol consumption (SHAC) procedure generates high, stable ethanol intake and blood ethanol concentrations in mice to levels consistent with definitions of binge drinking. The purpose of the present studies was to determine the effects of pharmacological manipulation of the opioidergic, glutamatergic, and γ-aminobutyric acid (GABA)ergic systems on… CONTINUE READING
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