Assessment and management of opioid withdrawal symptoms in buprenorphine-dependent subjects.

@article{San1992AssessmentAM,
  title={Assessment and management of opioid withdrawal symptoms in buprenorphine-dependent subjects.},
  author={L. I. M. Ying San and Jordi Cam{\'i} and Teresa P{\'e}rez Fern{\'a}ndez and J M Oll{\'e} and Josep Maria Peri and Marta Torrens},
  journal={British journal of addiction},
  year={1992},
  volume={87 1},
  pages={55-62}
}
The spontaneous physical dependence of buprenorphine was assessed in opioid addicts who switched from heroin to sublingual or intravenous buprenorphine. Twenty-two patients were randomly assigned to double-blind administration of methadone (n = 11) or placebo (n = 11) for 13 days after abrupt withdrawal of buprenorphine. Methadone was administered according… CONTINUE READING